Technology

Delivering the molecular future

The Check-Points molecular assays detect antibiotic resistance in gram negative bacteria through PCR-mediated identification and amplification followed by detection on a microarray platform. In one single test over 100 resistance markers can be identified with an accuracy down to one SNP. Evaluations by leading scientific experts have demonstrated excellent sensitivity and specificity for all species.

Assay flow

With the Check-Points molecular assay results can be obtained within 6 hours. Rapid detection is essential for administration of the optimal treatment and implementation of appropriate infection control measures.

Begin by isolating the total nucleic acid from your sample colonies using automated, magnetic bead or column-based methods. Proceed with the Check-Points molecular assay and visualize the results on the array. Using the E-Ads software, obtain an instant objective analysis of your results, helping you to avoid time-consuming subjective interpretation. The software automatically identifies the presence or absence of Carbapenemases, ESBL and AmpC as well as the specific resistance genes present.

Through our in-house expertise and contacts with leading international experts in the field we make sure to stay updated with the latest developments and trends in antibiotic resistance in gram negative bacteria. Doing so enables us to provide you with an assay incorporating the clinically prevalent Carbapenemases, ESBL and AmpC. The molecular future has only started.